On May 6, a by-election will be held for the electoral district of Nanaimo–Ladysmith (British Columbia) to fill a vacancy in the Canadian House of Commons.

On January 7, the Chief Electoral Officer of Canada, Stéphane Perrault, had received official notice from the Speaker of the House of Commons that the seat became vacant following the resignation of Sheila Malcolmson, who resigned on January 2 to run in a provincial byelection.

On March 24, Elections Canada declared the May election date and announced the opening of its local office in Nanaimo-Ladysmith.